Jake Michaelson Ph.D.

Jake Michaelson Ph.D.
Assistant Professor
Psychiatry
319-335-8066
365
MRC
Research Focus: 

The Michaelson lab investigates how variation in the genome affects the development and function of the mind. Our experience in genome informatics and statistical learning enables us to develop predictive models of gene-phenotype relationships based on high-throughput biological data sets. These models serve a dual purpose: 1) they improve our diagnostic/prognostic capabilities and 2) they illuminate the biological mechanisms that underlie psychiatric conditions. We have a particular interest in conditions that manifest themselves in childhood, such as autism spectrum disorders (ASD), attention deficit hyperactivity disorder (ADHD), specific language impairment (SLI), and developmental coordination disorder (DCD). These and other related conditions show striking comorbidity, and investigating their interrelationships will accelerate our understanding of their roots and potential treatments.

Research Mode: 
Clinical
Computational
Experimental
Research Paradigm(s): 
Chromatin and Histone Modifications
Gene-environment Interactions and Interplay
Genetic Association Studies
Machine Learning
Mutation
Network and Systems Biology
Sequencing and Variant Detection
Transcription and Transcriptional Regulation
Applications: 
Behavior and Mental Disorders
Development and Dysmorphology
Language
Nervous System
Organisms: 
Human
Rodent (mouse/rat)
College: 
Carver College of Medicine

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