Alex G Bassuk M.D., Ph.D.

Alex G Bassuk M.D., Ph.D.
Associate Professor
Pediatrics
319-356-7726
2167
ML
Lab phone: 
319-335-9686
Research Focus: 

Our laboratory is interested in understanding the basic mechanisms underlying both normal and disordered development of the nervous system. Our approach to these issues includes investigating the genetics of human neural tube defects (NTDs) and familial epilepsies, and elucidating the biology regulating neural stem cell development. The techniques used in our laboratory include genome wide linkage analysis (GWA), association studies, comparative genomic hybridization (CGH), copy number variation (CNV) analysis, transgenic mouse production, and cell culture. As part of our studies we have collected DNA samples from over 2000 patients and family members with congenital nervous system malformations, and several large families with autosomal recessive epilepsy syndromes.

Research Mode: 
Experimental
Research Paradigm(s): 
Cellular Signalling Pathways
Genetic Association Studies
Mutation
Sequencing and Variant Detection
Applications: 
Development and Dysmorphology
Nervous System
Organisms: 
Human
Rodent (mouse/rat)
College: 
Carver College of Medicine

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