People

Thomas L. Casavant

Thomas L. Casavant, Ph.D.

Title/Position
Professor
Phone
My research is divided among two areas: 1. High-Performance Parallel and Distributed Computing; and 2. Gene Discovery, Mapping, and Disease Linkage. Since 1986, my work in High-Performance Parallel and Distributed Computing has involved the theory, design, and prototyping of computer systems to...
Lucas Casten

Lucas Casten

Jacob Michaelson
Chi-Lien Cheng

Chi-Lien Cheng, Ph.D.

Title/Position
Professor
Phone
All land plants progress through a life cycle that alternates between two multicellular generations, the haploid gametophyte and the diploid sporophyte. In ferns, seedless vascular plants of the Monilophyte clade, both generations are free living. In addition to the normal life cycle using meiosis...
Josep M. Comeron

Josep M. Comeron, Ph.D.

Title/Position
Associate Professor
Phone
We apply a multidisciplinary approach-combining empirical work to obtain sequence data, large-scale genomic analyses, and the development of theoretical, analytical and computational tools-to investigate: 1) variation in the efficacy of natural selection among species and across genomes, 2) the...
Robert A. Cornell

Robert A. Cornell, Ph.D.

Title/Position
Professor
Phone
The neural crest, a transient population of multi-potent precursor cells exclusively found in vertebrate embryos, gives rise to neurons, glia, and melanocytes, among other cell types. The neural crest is thus an attractive model in which to explore universal cellular developmental events like fate...
Ben Darbro

Ben Darbro, M.D., Ph.D.

Title/Position
Associate Professor
Director of the Shivanand R. Patil Cytogenetics and Molecular Laboratory
Phone
My primary research interest is in the genetic determinants of intellectual disability (ID), formerly referred to as mental retardation (MR). I specifically study the roles of copy number variation and somatic structural variation in the context of a “genomic mutational burden” hypothesis of ID...
Arlene V. Drack

Arlene V. Drack, MD

Title/Position
Professor
Phone
Arlene V. Drack, M.D. is a clinician scientist specializing in juvenile inherited eye diseases. She is the inaugural Ronald V. Keech Associate Professor in Pediatric Ophthalmic Genetics at the University of Iowa Department of Ophthalmology and Visual Sciences. Her research focuses on inherited eye...
Adam J. Dupuy

Adam J. Dupuy, Ph.D.

Title/Position
Associate Professor
Phone
Human cancers arise through a multi-step genetic process that involves the loss of tumor suppressor genes and activation of proto-oncogenes. However, it is challenging to identify the causal mutations amid the large number of genetic and epigenetic changes typically found in human tumors. Mouse...
Daniel F. Eberl

Daniel F. Eberl, Ph.D.

Title/Position
Professor
Phone
We are interested in molecular and cellular mechanisms of how organisms detect sounds, and how they use information from sounds to direct their behavior. Drosophila males sing the "love song" to females by wing vibration. Females and males both hear the love song with their antennae and respond in a...
Hatem El-Shanti

Hatem El-Shanti, M.D.

Title/Position
Professor
Director, Division of Medical Genetics & Genomics
Phone
My research is interested in the identification of autosomal recessive genes through the utilization of the inbred populations of the Middle East. This research interest is not restricted to specific phenotypes, but was mainly targeting the study of Mendelian disorders. Currently, we use a similar...
Craig Ellermeier

Craig D. Ellermeier, Ph.D.

Title/Position
Professor
Phone
Work in the Ellermeier Lab focuses on how Gram-positive pathogens sense and respond to antibiotics and the innate immune system. Our work is primarily focused on the opportunistic human pathogen Clostridioides difficile. C. difficile is an anaerobic Gram-positive spore-forming pathogen that is the...
Albert J. Erives

Albert J. Erives, PhD

Title/Position
Associate Professor
Phone
Transcriptional enhancers are DNA sequences that specify inducible, spatiotemporal patterns of gene expression at most gene loci. Several complementary results from genomic studies have shown that the majority of functional sites in a genome correspond to transcriptional enhancer sequences, thus...
Jan S. Fassler

Jan S. Fassler, Ph.D.

Title/Position
Professor
Phone
S. cerevisiae is an important model for the study of environmental stress responses. My interest has been in probing the influence of the environment on the physical characteristics of cells by studying adaptive changes in transcription. All cells have the capacity to precisely modulate the...
John H. Fingert

John H. Fingert, M.D., PhD.

Title/Position
Professor
Phone
I am a board-certified ophthalmologist with fellowship training in glaucoma and I have a Ph.D. in ophthalmic genetics. My training and experience has provided me with broad clinical and laboratory expertise to investigate the genetic basis of optic nerve disease. My early research resulted in the...