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Peter Nagy Ph.D.
peter-nagyuiowadotedu
Assistant Professor of Molecular Pathology

1. Regulation of transcriptional elongation and termination through covalent modification of chromatin structure. 2. The role of allelic variation of histone methyltransferases in human disease.

Selected Publications

Nagy, P.L., Cleary, M.L., Brown, P.O., Lieb, J.D. Genomewide demarcation of RNA polymerase II transcription units revealed by physical fractionation of chromatin. Proc Natl Acad Sci USA. 100: 6364-9. 2003.

Firestein, R., Nagy, P.L., Daly, M., Huie, P., Conti, M., Cleary, M.L. Male infertility, impaired spermatogenesis, and azoospermia in mice deficient for the pseudophosphatase Sbf1. J Clin Invest. 109:1165-72, 2002.

Nagy P. L. , Griesenbeck J, Kornberg RD, Cleary ML. A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3. Proc Natl Acad Sci U S A. 99:90-4, 2002.

Weng, M., Nagy, P.L., and Zalkin, H. Identification of the Bacillus subtilis pur operon repressor. Proc. Natl. Acad. Sci. USA 92:7455-7459, 1995.

Nagy, P. L., Marolewsky, A., Benkovic, S., Zalkin, H. Formyltetrahydrofolate Hydrolase, a regulatory enzyme that functions to balance pools of tetrahydrofolate and one-carbon tetrahydrofolate adducts in Escherichia coli. J. Bacteriol. 177:1292-1298. 1995.